Priscilla Hsue, MD

Professor and Chief
Medicine
+1 628 206-8257

Professional Experience: Dr. Hsue trained in Internal Medicine in the Molecular Medicine Training Program at UC San Francisco and in Cardiovascular Medicine at UC San Francisco. She served as Chief Cardiology Fellow during this time. She has been on the faculty in the Department of Medicine at San Francisco General Hospital since 2002. She started the HIV Cardiology Clinic since March 2004 at the Positive Health Program at Ward 86, which is one of the first subspeciality clinics of its kind in the nation.

Research Interests:
- Cardiovascular complications of cocaine including aortic dissection, myocardial infarction, and cardiac arrest
- Pathogenesis of atherosclerosis in HIV-infected patients treated with antiretroviral therapy
- Clinical features and outcomes of acute coronary syndromes in HIV-infected patients
- Incidence and mechanisms of pulmonary hypertension in HIV-infected patients
- Dyslipidemia in HIV-infected patients

Publications: 

Extracellular vesicle TGF-ß1 is linked to cardiopulmonary dysfunction in HIV.

American journal of respiratory cell and molecular biology

Krishnamachary B, Mahajan A, Kumar A, Agarwal S, Mohan A, Chen L, Hsue P, Chalise P, Morris A, Dhillon NK

HIV Infection and the Risk of World Health Organization-Defined Sudden Cardiac Death.

Journal of the American Heart Association

Freiberg MS, Duncan MS, Alcorn C, Chang CH, Kundu S, Mumpuni A, Smith EK, Loch S, Bedigian A, Vittinghoff E, So-Armah K, Hsue PY, Justice AC, Tseng ZH

Intracranial vascular imaging detects arterial wall abnormalities in persons with treated HIV infection.

AIDS (London, England)

Chow FC, Callen A, Arechiga V, Saloner D, Narvid J, Hsue PY

Transmethylamine-N-Oxide Is Associated With Diffuse Cardiac Fibrosis in People Living With HIV.

Journal of the American Heart Association

Colaco NA, Wang TS, Ma Y, Scherzer R, Ilkayeva OR, Desvigne-Nickens P, Braunwald E, Hernandez AF, Butler J, Shah SH, Shah SJ, Hsue PY

Effect of Canakinumab vs Placebo on Survival Without Invasive Mechanical Ventilation in Patients Hospitalized With Severe COVID-19: A Randomized Clinical Trial.

JAMA

Caricchio R, Abbate A, Gordeev I, Meng J, Hsue PY, Neogi T, Arduino R, Fomina D, Bogdanov R, Stepanenko T, Ruiz-Seco P, Gónzalez-García A, Chen Y, Li Y, Whelan S, Noviello S, CAN-COVID Investigators

Characteristics of High-Titer Convalescent Plasma and Antibody Dynamics After Administration in Patients With Severe Coronavirus Disease 2019.

Open forum infectious diseases

Bainbridge ED, Hsue PY, Esensten JH, Lynch KL, Hendrickson CM, Doernberg SB, Fung M, Chin-Hong P, Di Germanio C, Norris PJ, Simmons G, Glidden DV, Luetkemeyer AF

Sudden Cardiac Death and Myocardial Fibrosis, Determined by Autopsy, in Persons with HIV.

The New England journal of medicine

Tseng ZH, Moffatt E, Kim A, Vittinghoff E, Ursell P, Connolly A, Olgin JE, Wong JK, Hsue PY

Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial.

The Lancet. Respiratory medicine

Tardif JC, Bouabdallaoui N, L'Allier PL, Gaudet D, Shah B, Pillinger MH, Lopez-Sendon J, da Luz P, Verret L, Audet S, Dupuis J, Denault A, Pelletier M, Tessier PA, Samson S, Fortin D, Tardif JD, Busseuil D, Goulet E, Lacoste C, Dubois A, Joshi AY, Waters DD, Hsue P, Lepor NE, Lesage F, Sainturet N, Roy-Clavel E, Bassevitch Z, Orfanos A, Stamatescu G, Grégoire JC, Busque L, Lavallée C, Hétu PO, Paquette JS, Deftereos SG, Levesque S, Cossette M, Nozza A, Chabot-Blanchet M, Dubé MP, Guertin MC, Boivin G, COLCORONA Investigators

Longitudinal Management and Outcomes of Acute Coronary Syndrome in Persons Living with HIV Infection.

European heart journal. Quality of care & clinical outcomes

Parks MM, Secemsky EA, Yeh RW, Shen C, Choi E, Kazi DS, Hsue PY

Lower Socioeconomic Status Associates with Greater Systemic and Arterial Inflammation in HIV.

Journal of acquired immune deficiency syndromes (1999)

Zhang L, Abohashem S, Osborne MT, Naddaf N, Park R, Moore K, Patrich T, Deeks SG, Hsue PY, Tawakol AA

Rapid implementation of a cohort for the study of post-acute sequelae of SARS-CoV-2 infection/COVID-19.

medRxiv : the preprint server for health sciences

Peluso MJ, Kelly JD, Lu S, Goldberg SA, Davidson MC, Mathur S, Durstenfeld MS, Spinelli MA, Hoh R, Tai V, Fehrman EA, Torres L, Hernandez Y, Williams MC, Arreguin MI, Bautista JA, Ngo LH, Deswal M, Munter SE, Martinez EO, Anglin KA, Romero MD, Tavs J, Rugart PR, Chen JY, Sans HM, Murray VW, Ellis PK, Donohue KC, Massachi JA, Weiss JO, Mehdi I, Pineda-Ramirez J, Tang AF, Wenger M, Assenzio M, Yuan Y, Krone M, Rutishauser RL, Rodriguez-Barraquer I, Greenhouse B, Sauceda JA, Gandhi M, Hsue PY, Henrich TJ, Deeks SG, Martin JN

Inflammation of the periodontium associates with risk of future cardiovascular events.

Journal of periodontology

Van Dyke TE, Kholy KE, Ishai A, Takx RAP, Mezue K, Abohashem SM, Ali A, Yuan N, Hsue P, Osborne MT, Tawakol A

Factors associated with worse cerebrovascular function in aging women with and at risk for HIV.

AIDS (London, England)

Chow FC, Ma Y, Manion M, Rupert A, Lambert-Messerlian G, Bushnell CD, Cedars MI, Sereti I, Sorond FA, Hsue PY, Tien PC

Methotrexate Decreases Tenofovir Exposure in Antiretroviral-Suppressed Individuals Living With HIV.

Journal of acquired immune deficiency syndromes (1999)

Gingrich D, Deitchman AN, Kantor A, Huang L, Stein JH, Currier JS, Hsue PY, Ribaudo HJ, Aweeka FT

Association of Viral Persistence and Atherosclerosis in Adults With Treated HIV Infection.

JAMA network open

McLaughlin MM, Ma Y, Scherzer R, Rahalkar S, Martin JN, Mills C, Milush J, Deeks SG, Hsue PY

Impact of polysubstance use on high-sensitivity cardiac troponin I over time in homeless and unstably housed women.

Drug and alcohol dependence

Riley ED, Vittinghoff E, Wu AHB, Coffin PO, Hsue PY, Kazi DS, Wade A, Braun C, Lynch KL

Methamphetamine and cardiac disease among people with HIV infection.

HIV medicine

Martin T, Gianella S, Franklin D, Hsue P, Smith DM

HIV X4 Variants Increase Arachidonate 5-Lipoxygenase in the Pulmonary Microenvironment and are associated with Pulmonary Arterial Hypertension.

Scientific reports

Almodovar S, Wade BE, Porter KM, Smith JM, Lopez-Astacio RA, Bijli K, Kang BY, Cribbs SK, Guidot DM, Molehin D, McNair BK, Pumarejo-Gomez L, Perez Hernandez J, Salazar EA, Martinez EG, Huang L, Kessing CF, Suarez-Martinez EB, Pruitt K, Hsue PY, Tyor WR, Flores SC, Sutliff RL

HIV and cardiovascular disease.

The lancet. HIV

So-Armah K, Benjamin LA, Bloomfield GS, Feinstein MJ, Hsue P, Njuguna B, Freiberg MS

Plasma tissue factor and immune activation are associated with carotid intima-media thickness progression in treated HIV infection.

AIDS (London, England)

Hsu DC, Ma YF, Narwan A, Rahalkar S, Rupert A, Scherzer R, Mills C, Deeks S, Sereti I, Hsue PY

Targeting Inflammation to Reduce Atherosclerotic Cardiovascular Risk in People With HIV Infection.

Journal of the American Heart Association

Titanji B, Gavegnano C, Hsue P, Schinazi R, Marconi VC

The Golden Compass Program: Overview of the Initial Implementation of a Comprehensive Program for Older Adults Living with HIV.

Journal of the International Association of Providers of AIDS Care

Greene M, Myers J, Tan JY, Blat C, O'Hollaren A, Quintanilla F, Hsue P, Shiels M, Hicks ML, Olson B, Grochowski J, Oskarsson J, Havlir D, Gandhi M

MicroRNA biomarkers associated with type 1 myocardial infarction in HIV-positive individuals.

AIDS (London, England)

Yuan N, Scherzer R, Tanriverdi K, Martin J, Rahalkar S, Hsue P

Atherosclerotic Cardiovascular Disease Risk Profile of Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate.

Open forum infectious diseases

Huhn GD, Shamblaw DJ, Baril JG, Hsue PY, Mills BL, Nguyen-Cleary T, McCallister S, Das M

Diastolic Dysfunction in Patients with Human Immunodeficiency Virus Receiving Antiretroviral Therapy: Results from the CHART Study.

Journal of cardiac failure

Butler J, Greene SJ, Shah SH, Shah SJ, Anstrom KJ, Kim RJ, Kalogeropoulos AP, Velazquez EJ, Hernandez AF, Desvigne-Nickens P, Scherzer R, Hsue PY, Braunwald E

Human Immunodeficiency Virus Infection and Incident Atrial Fibrillation.

Journal of the American College of Cardiology

Sardana M, Hsue PY, Tseng ZH, Vittinghoff E, Nah G, Dewland TA, Marcus GM

Seeing Is Believing: Nuclear Imaging of HIV Persistence.

Frontiers in immunology

Henrich TJ, Hsue PY, VanBrocklin H

Mortality following myocardial infarction among HIV-infected persons: the Center for AIDS Research Network Of Integrated Clinical Systems (CNICS).

BMC medicine

Feinstein MJ, Nance RM, Delaney JAC, Heckbert SR, Budoff MJ, Drozd DR, Burkholder GA, Willig JH, Mugavero MJ, Mathews WC, Moore RD, Eron JJ, Napravnik S, Hunt PW, Geng E, Hsue P, Peter I, Lober WB, Crothers K, Grunfeld C, Saag MS, Kitahata MM, Lloyd-Jones DM, Crane HM

Periodontal Disease Associates With Arterial Inflammation Via Potentiation of a Hematopoietic-Arterial Axis.

JACC. Cardiovascular imaging

Ishai A, Osborne MT, El Kholy K, Takx RAP, Ali A, Yuan N, Hsue P, Van Dyke TE, Tawakol A

HIV infection and coronary heart disease: mechanisms and management.

Nature reviews. Cardiology

Hsue PY, Waters DD

Characteristics, Prevention, and Management of Cardiovascular Disease in People Living With HIV: A Scientific Statement From the American Heart Association.

Circulation

Feinstein MJ, Hsue PY, Benjamin LA, Bloomfield GS, Currier JS, Freiberg MS, Grinspoon SK, Levin J, Longenecker CT, Post WS

Safety and Impact of Low-Dose Methotrexate on Endothelial Function and Inflammation in Individuals with Treated Human Immunodeficiency Virus: AIDS Clinical Trials Group Study A5314.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Hsue PY, Ribaudo HJ, Deeks SG, Bell T, Ridker PM, Fichtenbaum C, Daar ES, Havlir D, Yeh E, Tawakol A, Lederman M, Currier JS, Stein JH

Carnitine Is Associated With Atherosclerotic Risk and Myocardial Infarction in HIV -Infected Adults.

Journal of the American Heart Association

Sinha A, Ma Y, Scherzer R, Rahalkar S, Neilan BD, Crane H, Drozd D, Martin J, Deeks SG, Hunt P, Hsue PY

Unique Circulating MicroRNA Profiles in HIV Infection.

Journal of acquired immune deficiency syndromes (1999)

Narla V, Bhakta N, Freedman JE, Tanriverdi K, Maka K, Deeks SG, Ganz P, Hsue P

Introduction to Cardiovascular Issues in HIV.

The Canadian journal of cardiology

Waters DD, Hsue PY

IL-1ß Inhibition Reduces Atherosclerotic Inflammation in HIV Infection.

Journal of the American College of Cardiology

Hsue PY, Li D, Ma Y, Ishai A, Manion M, Nahrendorf M, Ganz P, Ridker PM, Deeks SG, Tawakol A

Brachial Artery Echogenicity and Grayscale Texture Changes in HIV-Infected Individuals Receiving Low-Dose Methotrexate.

Arteriosclerosis, thrombosis, and vascular biology

Stein JH, Yeh E, Weber JM, Korcarz C, Ridker PM, Tawakol A, Hsue PY, Currier JS, Ribaudo H, Mitchell CKC

Lipid Abnormalities in Persons Living With HIV Infection.

The Canadian journal of cardiology

Waters DD, Hsue PY

Adjudicated Heart Failure in HIV-Infected and Uninfected Men and Women.

Journal of the American Heart Association

Feinstein MJ, Steverson AB, Ning H, Pawlowski AE, Schneider D, Ahmad FS, Sanders JM, Sinha A, Nance RM, Achenbach CJ, Christopher Delaney JA, Heckbert SR, Shah SJ, Hanna DB, Hsue PY, Bloomfield GS, Longenecker CT, Crane HM, Lloyd-Jones DM

Inflammation, Immunity, and Infection in Atherothrombosis: JACC Review Topic of the Week.

Journal of the American College of Cardiology

Libby P, Loscalzo J, Ridker PM, Farkouh ME, Hsue PY, Fuster V, Hasan AA, Amar S

Differentiation of Type 1 and Type 2 Myocardial Infarctions Among HIV-Infected Patients Requires Adjudication Due to Overlap in Risk Factors.

AIDS research and human retroviruses

Nance RM, Crane HM, Ritchings C, Rosenblatt L, Budoff M, Heckbert SR, Drozd DR, Mathews WC, Geng E, Hunt PW, Feinstein MJ, Moore RD, Hsue P, Eron JJ, Burkholder GA, Rodriguez B, Mugavero MJ, Saag MS, Kitahata MM, Delaney JAC

Association of Biomarker Clusters With Cardiac Phenotypes and Mortality in Patients With HIV Infection.

Circulation. Heart failure

Scherzer R, Shah SJ, Secemsky E, Butler J, Grunfeld C, Shlipak MG, Hsue PY

Increased Echocardiographic Pulmonary Pressure in HIV-infected and -uninfected Individuals in the Veterans Aging Cohort Study.

American journal of respiratory and critical care medicine

Brittain EL, Duncan MS, Chang J, Patterson OV, DuVall SL, Brandt CA, So-Armah KA, Goetz M, Akgun K, Crothers K, Zola C, Kim J, Gibert C, Pisani M, Morris A, Hsue P, Tindle HA, Justice A, Freiberg M

Diastolic Dysfunction in Individuals With Human Immunodeficiency Virus Infection: Literature Review, Rationale and Design of the Characterizing Heart Function on Antiretroviral Therapy (CHART) Study.

Journal of cardiac failure

Butler J, Kalogeropoulos AP, Anstrom KJ, Hsue PY, Kim RJ, Scherzer R, Shah SJ, Shah SH, Velazquez EJ, Hernandez AF, Desvigne-Nickens P, Braunwald E

Comorbidities Among US Patients With Prevalent HIV Infection-A Trend Analysis.

The Journal of infectious diseases

Gallant J, Hsue PY, Shreay S, Meyer N

Heart failure in persons living with HIV infection.

Current opinion in HIV and AIDS

Hsue PY, Waters DD

Projections of non-communicable disease and health care costs among HIV-positive persons in Italy and the U.S.A.: A modelling study.

PloS one

Smit M, Cassidy R, Cozzi-Lepri A, Quiros-Roldan E, Girardi E, Mammone A, Antinori A, Saracino A, Bai F, Rusconi S, Magnani G, Castelli F, Hsue P, d'Arminio Monforte A, Hallett TB

Healthcare utilization and direct costs of non-infectious comorbidities in HIV-infected patients in the USA.

Current medical research and opinion

Gallant J, Hsue P, Budd D, Meyer N

CHA2DS2-VASc Score, Warfarin Use, and Risk for Thromboembolic Events Among HIV-Infected Persons With Atrial Fibrillation.

Journal of acquired immune deficiency syndromes (1999)

Chau KH, Scherzer R, Grunfeld C, Hsue PY, Shlipak MG

Utility of 2013 American College of Cardiology/American Heart Association Cholesterol Guidelines in HIV-Infected Adults With Carotid Atherosclerosis.

Circulation. Cardiovascular imaging

Phan BAP, Weigel B, Ma Y, Scherzer R, Li D, Hur S, Kalapus SC, Deeks S, Hsue P

Association of Tenofovir Use With Risk of Incident Heart Failure in HIV-Infected Patients.

Journal of the American Heart Association

Chen R, Scherzer R, Hsue PY, Jotwani V, Estrella MM, Horberg MA, Grunfeld C, Shlipak MG

Greater Risk of Stroke of Undetermined Etiology in a Contemporary HIV-Infected Cohort Compared with Uninfected Individuals.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

Chow FC, Price RW, Hsue PY, Kim AS

Types of Myocardial Infarction Among Human Immunodeficiency Virus-Infected Individuals in the United States.

JAMA cardiology

Crane HM, Paramsothy P, Drozd DR, Nance RM, Delaney JA, Heckbert SR, Budoff MJ, Burkholder GA, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Eron JJ, Napravnik S, Hunt PW, Geng E, Hsue P, Rodriguez C, Peter I, Barnes GS, McReynolds J, Lober WB, Crothers K, Feinstein MJ, Grunfeld C, Saag MS, Kitahata MM

Association of Arterial and Lymph Node Inflammation With Distinct Inflammatory Pathways in Human Immunodeficiency Virus Infection.

JAMA cardiology

Tawakol A, Ishai A, Li D, Takx RA, Hur S, Kaiser Y, Pampaloni M, Rupert A, Hsu D, Sereti I, Fromentin R, Chomont N, Ganz P, Deeks SG, Hsue PY

Higher prevalence of detectable troponin I among cocaine-users without known cardiovascular disease.

Drug and alcohol dependence

Riley ED, Hsue PY, Vittinghoff E, Wu AH, Coffin PO, Moore PK, Lynch KL

Role of T-Cell Dysfunction, Inflammation, and Coagulation in Microvascular Disease in HIV.

Journal of the American Heart Association

Sinha A, Ma Y, Scherzer R, Hur S, Li D, Ganz P, Deeks SG, Hsue PY

Plasma IL-6 levels are independently associated with atherosclerosis and mortality in HIV-infected individuals on suppressive antiretroviral therapy.

AIDS (London, England)

Hsu DC, Ma YF, Hur S, Li D, Rupert A, Scherzer R, Kalapus SC, Deeks S, Sereti I, Hsue PY

Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension.

The Journal of clinical investigation

Bertero T, Oldham WM, Cottrill KA, Pisano S, Vanderpool RR, Yu Q, Zhao J, Tai Y, Tang Y, Zhang YY, Rehman S, Sugahara M, Qi Z, Gorcsan J, Vargas SO, Saggar R, Saggar R, Wallace WD, Ross DJ, Haley KJ, Waxman AB, Parikh VN, De Marco T, Hsue PY, Morris A, Simon MA, Norris KA, Gaggioli C, Loscalzo J, Fessel J, Chan SY

Immunologic profiles distinguish aviremic HIV-infected adults.

AIDS (London, England)

Ramirez CM, Sinclair E, Epling L, Lee SA, Jain V, Hsue PY, Hatano H, Conn D, Hecht FM, Martin JN, McCune JM, Deeks SG, Hunt PW

HIV and Hepatitis C-Coinfected Patients Have Lower Low-Density Lipoprotein Cholesterol Despite Higher Proprotein Convertase Subtilisin Kexin 9 (PCSK9): An Apparent "PCSK9-Lipid Paradox".

Journal of the American Heart Association

Kohli P, Ganz P, Ma Y, Scherzer R, Hur S, Weigel B, Grunfeld C, Deeks S, Wasserman S, Scott R, Hsue PY

PCSK9 Inhibitors for Statin Intolerance?

JAMA

Waters DD, Hsue PY, Bangalore S

Inflammation and Fibrosis in HIV: Getting to the Heart of the Matter.

Circulation. Cardiovascular imaging

Hsue PY, Tawakol A

Endothelin-1 Predicts Hemodynamically Assessed Pulmonary Arterial Hypertension in HIV Infection.

PloS one

Parikh RV, Ma Y, Scherzer R, Heringer AS, Macgregor JS, Martin JN, Deeks SG, Ganz P, Hsue PY

Cerebral vasoreactivity is impaired in treated, virally suppressed HIV-infected individuals.

AIDS (London, England)

Chow FC, Boscardin WJ, Mills C, Ko N, Carroll C, Price RW, Deeks S, Sorond FA, Hsue PY

Patterns of Cardiovascular Mortality for HIV-Infected Adults in the United States: 1999 to 2013.

The American journal of cardiology

Feinstein MJ, Bahiru E, Achenbach C, Longenecker CT, Hsue P, So-Armah K, Freiberg MS, Lloyd-Jones DM

Brief Report: Coordinated Modulation of Circulating miR-21 in HIV, HIV-Associated Pulmonary Arterial Hypertension, and HIV/Hepatitis C Virus Coinfection.

Journal of acquired immune deficiency syndromes (1999)

Parikh VN, Park J, Nikolic I, Channick R, Yu PB, De Marco T, Hsue PY, Chan SY

Novel Biomarkers of Cardiac Stress, Cardiovascular Dysfunction, and Outcomes in HIV-Infected Individuals.

JACC. Heart failure

Secemsky EA, Scherzer R, Nitta E, Wu AH, Lange DC, Deeks SG, Martin JN, Snider J, Ganz P, Hsue PY

Mitral Annular and Coronary Artery Calcification Are Associated with Mortality in HIV-Infected Individuals.

PloS one

Lange DC, Glidden D, Secemsky EA, Ordovas K, Deeks SG, Martin JN, Bolger AF, Hsue PY

Correction: A novel minimally-invasive method to sample human endothelial cells for molecular profiling.

PloS one

Waldo SW, Brenner DA, McCabe JM, De la Cruz M, Long B, Narla VA, Park J, Kulkarni A, Sinclair E, Chan SY, Schick SF, Malik N, Ganz P, Hsue PY

A novel minimally-invasive method to sample human endothelial cells for molecular profiling.

PloS one

Waldo SW, Brenner DA, McCabe JM, Dela Cruz M, Long B, Narla VA, Park J, Kulkarni A, Sinclair E, Chan SY, Schick SF, Malik N, Ganz P, Hsue PY

The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD4+ T cell recovery: a randomized crossover trial.

PloS one

Somsouk M, Dunham RM, Cohen M, Albright R, Abdel-Mohsen M, Liegler T, Lifson J, Piatak M, Gorelick R, Huang Y, Wu Y, Hsue PY, Martin JN, Deeks SG, McCune JM, Hunt PW

Impact of female sex on lipid lowering, clinical outcomes, and adverse effects in atorvastatin trials.

The American journal of cardiology

Hsue PY, Bittner VA, Betteridge J, Fayyad R, Laskey R, Wenger NK, Waters DD

Effect of CD4+ cell count and viral suppression on risk of ischemic stroke in HIV infection.

AIDS (London, England)

Chow FC, Bacchetti P, Kim AS, Price RW, Hsue PY

Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis.

Journal of the American Heart Association

Hsue PY, Scherzer R, Grunfeld C, Imboden J, Wu Y, Del Puerto G, Nitta E, Shigenaga J, Schnell Heringer A, Ganz P, Graf J

The authors reply.

American journal of epidemiology

Crane HM, Heckbert SR, Drozd DR, Budoff MJ, Delaney JA, Rodriguez C, Paramsothy P, Lober WB, Burkholder G, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Napravnik S, Eron JJ, Hunt P, Geng E, Hsue P, Barnes GS, McReynolds J, Peter I, Grunfeld C, Saag MS, Kitahata MM

HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality.

PLoS pathogens

Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, Huang Y, Hecht FM, Martin JN, McCune JM, Moreno S, Deeks SG

Lessons learned from the design and implementation of myocardial infarction adjudication tailored for HIV clinical cohorts.

American journal of epidemiology

Crane HM, Heckbert SR, Drozd DR, Budoff MJ, Delaney JA, Rodriguez C, Paramsothy P, Lober WB, Burkholder G, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Napravnik S, Eron JJ, Hunt P, Geng E, Hsue P, Barnes GS, McReynolds J, Peter I, Grunfeld C, Saag MS, Kitahata MM

Impact of HIV on CD8+ T cell CD57 expression is distinct from that of CMV and aging.

PloS one

Lee SA, Sinclair E, Hatano H, Hsue PY, Epling L, Hecht FM, Bangsberg DR, Martin JN, McCune JM, Deeks SG, Hunt PW

Increased levels of asymmetric dimethylarginine are associated with pulmonary arterial hypertension in HIV infection.

AIDS (London, England)

Parikh RV, Scherzer R, Nitta EM, Leone A, Hur S, Mistry V, Macgregor JS, Martin JN, Deeks SG, Ganz P, Hsue PY

Effect of left ventricular dysfunction and viral load on risk of sudden cardiac death in patients with human immunodeficiency virus.

The American journal of cardiology

Moyers BS, Secemsky EA, Vittinghoff E, Wong JK, Havlir DV, Hsue PY, Tseng ZH

Reply to Karch et al.

The Journal of infectious diseases

Hatano H, Bacchetti P, Hsue PY, Deeks SG

Physician accuracy in interpreting potential ST-segment elevation myocardial infarction electrocardiograms.

Journal of the American Heart Association

McCabe JM, Armstrong EJ, Ku I, Kulkarni A, Hoffmayer KS, Bhave PD, Waldo SW, Hsue P, Stein JC, Marcus GM, Kinlay S, Ganz P

Prehypertension, hypertension, and the risk of acute myocardial infarction in HIV-infected and -uninfected veterans.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Armah KA, Chang CC, Baker JV, Ramachandran VS, Budoff MJ, Crane HM, Gibert CL, Goetz MB, Leaf DA, McGinnis KA, Oursler KK, Rimland D, Rodriguez-Barradas MC, Sico JJ, Warner AL, Hsue PY, Kuller LH, Justice AC, Freiberg MS

Long-term outcomes of patients sent emergently to the catheterization laboratory for possible primary percutaneous coronary intervention.

The American journal of cardiology

Turner TE, Waldo SW, Kulkarni A, Armstrong EJ, Hoffmayer KS, Kinlay S, Hsue P, Ganz P, McCabe JM

Increase in 2-long terminal repeat circles and decrease in D-dimer after raltegravir intensification in patients with treated HIV infection: a randomized, placebo-controlled trial.

The Journal of infectious diseases

Hatano H, Strain MC, Scherzer R, Bacchetti P, Wentworth D, Hoh R, Martin JN, McCune JM, Neaton JD, Tracy RP, Hsue PY, Richman DD, Deeks SG

Clinical characteristics and reperfusion times among patients with an isolated posterior myocardial infarction.

The Journal of invasive cardiology

Waldo SW, Armstrong EJ, Kulkarni A, Hoffmayer KS, Hsue P, Ganz P, McCabe JM

Emergency medical service utilization and door-to-balloon time for HIV-infected individuals with ST-elevation myocardial infarction.

International journal of cardiology

Brenner DA, Dela Cruz M, Thomas K, McCabe JM, Ganz P, Hsue PY, Waldo SW

Elevated levels of asymmetric dimethylarginine are associated with lower CD4+ count and higher viral load in HIV-infected individuals.

Atherosclerosis

Parikh RV, Scherzer R, Grunfeld C, Nitta EM, Leone A, Martin JN, Deeks SG, Ganz P, Hsue PY

Atrial fibrillation and atrial flutter in human immunodeficiency virus-infected persons: incidence, risk factors, and association with markers of HIV disease severity.

Journal of the American College of Cardiology

Hsu JC, Li Y, Marcus GM, Hsue PY, Scherzer R, Grunfeld C, Shlipak MG

Comparison of clinical characteristics and outcomes of cardiac arrest survivors having versus not having coronary angiography.

The American journal of cardiology

Waldo SW, Armstrong EJ, Kulkarni A, Hoffmayer K, Kinlay S, Hsue P, Ganz P, McCabe JM

PR Interval and sudden cardiac death in patients with HIV infection.

The Journal of infectious diseases

Tseng ZH, Moyers B, Secemsky EA, Havlir DV, Hsue PY

A randomized controlled trial assessing the effects of raltegravir intensification on endothelial function in treated HIV infection.

Journal of acquired immune deficiency syndromes (1999)

Hatano H, Scherzer R, Wu Y, Harvill K, Maka K, Hoh R, Sinclair E, Palmer S, Martin JN, Busch MP, Deeks SG, Hsue PY

Doppler echocardiography does not accurately estimate pulmonary artery systolic pressure in HIV-infected patients.

AIDS (London, England)

Selby VN, Scherzer R, Barnett CF, MacGregor JS, Morelli J, Donovan C, Deeks SG, Martin JN, Hsue PY

Impact of door-to-activation time on door-to-balloon time in primary percutaneous coronary intervention for ST-segment elevation myocardial infarctions: a report from the Activate-SF registry.

Circulation. Cardiovascular quality and outcomes

McCabe JM, Armstrong EJ, Hoffmayer KS, Bhave PD, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P

Prevalence and factors associated with false-positive ST-segment elevation myocardial infarction diagnoses at primary percutaneous coronary intervention–capable centers: a report from the Activate-SF registry.

Archives of internal medicine

McCabe JM, Armstrong EJ, Kulkarni A, Hoffmayer KS, Bhave PD, Garg S, Patel A, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P

Immunologic basis of cardiovascular disease in HIV-infected adults.

The Journal of infectious diseases

Hsue PY, Deeks SG, Hunt PW

The association of CD4+ T-cell counts and cardiovascular risk in treated HIV disease.

AIDS (London, England)

Ho JE, Scherzer R, Hecht FM, Maka K, Selby V, Martin JN, Ganz P, Deeks SG, Hsue PY

Sudden cardiac death in patients with human immunodeficiency virus infection.

Journal of the American College of Cardiology

Tseng ZH, Secemsky EA, Dowdy D, Vittinghoff E, Moyers B, Wong JK, Havlir DV, Hsue PY

The exposure-dependent effects of aged secondhand smoke on endothelial function.

Journal of the American College of Cardiology

Frey PF, Ganz P, Hsue PY, Benowitz NL, Glantz SA, Balmes JR, Schick SF

A role for cytomegalovirus-specific CD4+CX3CR1+ T cells and cytomegalovirus-induced T-cell immunopathology in HIV-associated atherosclerosis.

AIDS (London, England)

Sacre K, Hunt PW, Hsue PY, Maidji E, Martin JN, Deeks SG, Autran B, McCune JM

Carotid Intima-Media Thickness Progression in HIV-Infected Adults Occurs Preferentially at the Carotid Bifurcation and Is Predicted by Inflammation.

Journal of the American Heart Association

Hsue PY, Scherzer R, Hunt PW, Schnell A, Bolger AF, Kalapus SC, Maka K, Martin JN, Ganz P, Deeks SG

Delaying primary percutaneous coronary intervention for computed tomographic scans in the emergency department.

The American journal of cardiology

Armstrong EJ, Kulkarni AR, Hoffmayer KS, Bhave PD, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P, McCabe JM

HIV infection is associated with decreased thrombin generation.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Hsue PY, Scherzer R, Grunfeld C, Nordstrom SM, Schnell A, Kohl LP, Nitta E, Martin JN, Deeks SG, Weiss EJ

Human Immunodeficiency Virus nef signature sequences are associated with pulmonary hypertension.

AIDS research and human retroviruses

Almodovar S, Knight R, Allshouse AA, Roemer S, Lozupone C, McDonald D, Widmann J, Voelkel NF, Shelton RJ, Suarez EB, Hammer KW, Goujard C, Petrosillo N, Simonneau G, Hsue PY, Humbert M, Flores SC

Increased CD34+/KDR+ cells are not associated with carotid artery intima-media thickness progression in chronic HIV-positive subjects.

Antiviral therapy

Papasavvas E, Hsue P, Reynolds G, Pistilli M, Hancock A, Martin JN, Deeks SG, Montaner LJ

Carotid intima-media thickness among human immunodeficiency virus-infected patients without coronary calcium.

The American journal of cardiology

Hsue PY, Ordovas K, Lee T, Reddy G, Gotway M, Schnell A, Ho JE, Selby V, Madden E, Martin JN, Deeks SG, Ganz P, Waters DD

Improvement in revascularization time after creation of a coronary catheterization laboratory at a public hospital.

Archives of internal medicine

Secemsky EA, Lange D, Ho JE, Brayton K, Ganz PA, Farr G, Macgregor JS, Hsue PY

Hemodynamic and arrhythmogenic effects of cocaine in hypertensive individuals.

Journal of clinical hypertension (Greenwich, Conn.)

Secemsky E, Lange D, Waters DD, Goldschlager NF, Hsue PY

Pulmonary hypertension in HIV-infected individuals.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Hsue PY, Bolger AF, Martin JN

Pathogenesis of HIV-associated pulmonary hypertension: potential role of HIV-1 Nef.

Proceedings of the American Thoracic Society

Almodovar S, Hsue PY, Morelli J, Huang L, Flores SC

Association of vitamin D insufficiency with carotid intima-media thickness in HIV-infected persons.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Choi AI, Lo JC, Mulligan K, Schnell A, Kalapus SC, Li Y, Hunt PW, Martin JN, Deeks SG, Hsue PY

Beta-blockers for chest pain associated with recent cocaine use.

Archives of internal medicine

Rangel C, Shu RG, Lazar LD, Vittinghoff E, Hsue PY, Marcus GM

Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease.

PloS one

Naeger DM, Martin JN, Sinclair E, Hunt PW, Bangsberg DR, Hecht F, Hsue P, McCune JM, Deeks SG

Impact of HIV infection on diastolic function and left ventricular mass.

Circulation. Heart failure

Hsue PY, Hunt PW, Ho JE, Farah HH, Schnell A, Hoh R, Martin JN, Deeks SG, Bolger AF

Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients.

AIDS (London, England)

Hsue PY, Hunt PW, Wu Y, Schnell A, Ho JE, Hatano H, Xie Y, Martin JN, Ganz P, Deeks SG

Cardiovascular manifestations of HIV infection.

Heart (British Cardiac Society)

Ho JE, Hsue PY

Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis.

AIDS (London, England)

Hsue PY, Hunt PW, Schnell A, Kalapus SC, Hoh R, Ganz P, Martin JN, Deeks SG

Rheumatoid arthritis: model of systemic inflammation driving atherosclerosis.

Circulation journal : official journal of the Japanese Circulation Society

Ku IA, Imboden JB, Hsue PY, Ganz P

Criteria for evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association.

Circulation

Hlatky MA, Greenland P, Arnett DK, Ballantyne CM, Criqui MH, Elkind MS, Go AS, Harrell FE, Hong Y, Howard BV, Howard VJ, Hsue PY, Kramer CM, McConnell JP, Normand SL, O'Donnell CJ, Smith SC, Wilson PW

Ezetimibe alone reduces low-density lipoprotein cholesterol in HIV-infected patients receiving combination antiretroviral therapy.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Wohl DA, Waters D, Simpson RJ, Richard S, Schnell A, Napravnik S, Keys J, Eron JJ, Hsue P

Screening and assessment of coronary heart disease in HIV-infected patients.

Circulation

Hsue PY, Squires K, Bolger AF, Capili B, Mensah GA, Temesgen Z, Wanke CA, Wohl DA

State of the science conference: Initiative to decrease cardiovascular risk and increase quality of care for patients living with HIV/AIDS: executive summary.

Circulation

Grinspoon SK, Grunfeld C, Kotler DP, Currier JS, Lundgren JD, Dubé MP, Lipshultz SE, Hsue PY, Squires K, Schambelan M, Wilson PW, Yarasheski KE, Hadigan CM, Stein JH, Eckel RH

Role of HIV and human herpesvirus-8 infection in pulmonary arterial hypertension.

AIDS (London, England)

Hsue PY, Deeks SG, Farah HH, Palav S, Ahmed SY, Schnell A, Ellman AB, Huang L, Dollard SC, Martin JN

Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy.

The Journal of infectious diseases

Hunt PW, Brenchley J, Sinclair E, McCune JM, Roland M, Page-Shafer K, Hsue P, Emu B, Krone M, Lampiris H, Douek D, Martin JN, Deeks SG

Cardiac arrest in patients who smoke crack cocaine.

The American journal of cardiology

Hsue PY, McManus D, Selby V, Ren X, Pillutla P, Younes N, Goldschlager N, Waters DD

Increased carotid intima-media thickness in HIV patients is associated with increased cytomegalovirus-specific T-cell responses.

AIDS (London, England)

Hsue PY, Hunt PW, Sinclair E, Bredt B, Franklin A, Killian M, Hoh R, Martin JN, McCune JM, Waters DD, Deeks SG

The relationship between nucleoside analogue treatment duration, insulin resistance, and fasting arterialized lactate level in patients with HIV infection.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Lo JC, Kazemi MR, Hsue PY, Martin JN, Deeks SG, Schambelan M, Mulligan K

Role of thrombotic and fibrinolytic factors in acute coronary syndromes.

Progress in cardiovascular diseases

Saigo M, Hsue PY, Waters DD

Progression of atherosclerosis as assessed by carotid intima-media thickness in patients with HIV infection.

Circulation

Hsue PY, Lo JC, Franklin A, Bolger AF, Martin JN, Deeks SG, Waters DD

Clinical features of acute coronary syndromes in patients with human immunodeficiency virus infection.

Circulation

Hsue PY, Giri K, Erickson S, MacGregor JS, Younes N, Shergill A, Waters DD

Acute aortic dissection related to crack cocaine.

Circulation

Hsue PY, Salinas CL, Bolger AF, Benowitz NL, Waters DD

A 19F-NMR study of the membrane-binding region of D-lactate dehydrogenase of Escherichia coli.

Protein science : a publication of the Protein Society

Sun ZY, Truong HT, Pratt EA, Sutherland DC, Kulig CE, Homer RJ, Groetsch SM, Hsue PY, Ho C