Laurence Huang, MD

Clinical Professor
Medicine
+1 415 476-4082 ext. 406

I am a pulmonary and critical care medicine specialist with a research focus on pulmonary diseases affecting persons with HIV. I am PI/Co-PI on these main studies:

I AM OLD and I AM OLD-DA (renewal): The Inflammation, Aging, Microbes and Obstructive Lung Disease (I AM OLD) Study and The Inflammation, Aging, Microbes, Obstructive Lung Disease, and Diffusion Abnormalities (I AM OLD-DA) Study is a multi-cohort study whose goal is to examine potential mechanisms for development of obstructive lung disease and progression of airflow obstruction and diffusion abnormalities in a multi-national cohort of HIV-infected subjects with opportunistic pneumonia.

I AM GOLD: The Integrated Analysis of Microbial and Genomic data in Obstructive Lung Disease (I AM GOLD) Study is a multi-cohort study whose goal is to examine airway microbial communities (the lung microbiome) and inflammatory gene expression markers at the time of acute infection and during chronic stable disease that are associated with HIV-associated COPD and lung function decline in HIV and to perform integrative analyses of the airway microbiome, microbial and human transcriptome, metabolome and lung radiographic changes in HIV+ COPD.

Recent, former studies:
IHOP: The International HIV-associated Opportunistic Pneumonias (IHOP) Study is a multi-national cohort study whose goal is to improve our understanding of the epidemiology, etiology, and outcome of pneumonias in persons with HIV infection. IHOP was part of the Lung HIV Study, a collaborative multi-R01 consortium established by the National Heart, Lung, and Blood Institute (NHLBI) to examine a diverse range of infectious and non-infectious pulmonary diseases in HIV-infected persons.

Lung MicroCHIP: The Lung Microbiome in Cohorts of HIV-Infected Persons (Lung MicroChip) Study is a multi-cohort study whose goal is to examine the composition and function of the lung microbiome in persons with HIV. Lung MicroChip was part of the Lung HIV Microbiome Project, a collaborative multi-U01 consortium established by the NHLBI to study the lung microbiome in HIV infection.

I am also involved in training the next generation of clinical and translational researchers at both fellowship and junior faculty levels, including through the following NIH-funded training programs:

Multidisciplinary Training Program in Lung Disease (NIH T32 HL007185): This is a continuation of the UCSF Multidisciplinary Training Program in Lung Disease, which provides training in basic and clinical sciences important to the respiratory system. The program draws on the basic and clinical research skills of the broad group of faculty at UCSF addressing questions directly relevant to lung biology and disease. The grant is to accommodate a total of 13 postdoctoral trainees, including both MDs and PhDs. The main program is an actual research experience under the close supervision of a Preceptor and a review committee selected on the basis of the experimental approaches of the trainee. These approaches include disciplines applicable at the molecular, cellular, tissue, organ, whole animal, clinical, or population levels.

CHIC (NIH K12 HL143961): The UCSF Career Development Program in Cardiopulmonary, Hematologic, and Immunologic Comorbidities of HIV (CHIC) is a K12 training grant whose goals are: (1) To recruit MD, MD/PhD and PhD scholars dedicated to independent research careers conducting clinical and translational research in HIV-related heart, lung, and blood research; (2) To design, implement, and monitor individualized and tailored research training and career development of these scholars using an interdisciplinary, team-science, and team-mentoring approach that combines didactic training in research methods with supervised research under the mentorship of an experienced faculty mentor and mentoring team; (3) To produce the ‘next generation’ of researchers in HIV-associated heart, lung and blood diseases.

Publications: 

Association between Pain, Pulmonary Function, and Respiratory Symptoms in People with HIV.

Journal of acquired immune deficiency syndromes (1999)

Singhvi DG, Nouraie M, Kessinger C, McMahon DK, Weinman R, Crothers K, Huang L, Bon J, Morris A, Merlin J

Markers of inflammation and immune activation are associated with lung function in a multicenter cohort of persons with HIV.

AIDS (London, England)

Jan AK, Moore JV, Wang RJ, Mcging M, Farr CK, Moisi D, Hartman-Filson M, Kerruish R, Jeon D, Lewis E, Crothers K, Lederman MM, Hunt PW, Huang L

Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens.

Nature communications

Walter ND, Born SEM, Robertson GT, Reichlen M, Dide-Agossou C, Ektnitphong VA, Rossmassler K, Ramey ME, Bauman AA, Ozols V, Bearrows SC, Schoolnik G, Dolganov G, Garcia B, Musisi E, Worodria W, Huang L, Davis JL, Nguyen NV, Nguyen HV, Nguyen ATV, Phan H, Wilusz C, Podell BK, Sanoussi ND, de Jong BC, Merle CS, Affolabi D, McIlleron H, Garcia-Cremades M, Maidji E, Eshun-Wilson F, Aguilar-Rodriguez B, Karthikeyan D, Mdluli K, Bansbach C, Lenaerts AJ, Savic RM, Nahid P, Vásquez JJ, Voskuil MI

Association of monocyte migration marker CD11b with pulmonary function in people living with HIV.

Journal of acquired immune deficiency syndromes (1999)

Kuniholm MH, Bramah-Lawani M, Fitzpatrick M, Nouraie M, Qin S, Huang L, Vallejo AN, Landay AL, Morris A

C-Reactive Protein for Active Tuberculosis Among Inpatients without HIV in Uganda: A Diagnostic Accuracy Study.

Journal of clinical microbiology

Meyer AJ, Ochom E, Turimumahoro P, Byanyima P, Sanyu I, Lalitha R, Kaswabuli S, Andama A, Walter ND, Katamba A, Cattamanchi A, Worodria W, Huang L, Yoon C, Davis JL

Chronic obstructive pulmonary disease in HIV.

Expert review of respiratory medicine

Byanova K, Kunisaki KM, Vasquez J, Huang L

Community-Acquired Pneumonia and Risk of Cardiovascular Events in People Living With HIV.

Journal of the American Heart Association

Zifodya JS, Duncan MS, So-Armah KA, Attia EF, Akgün KM, Rodriguez-Barradas MC, Marconi VC, Budoff MJ, Bedimo RJ, Alcorn CW, Soo Hoo GW, Butt AA, Kim JW, Sico JJ, Tindle HA, Huang L, Tate JP, Justice AC, Freiberg MS, Crothers K

Associations of marijuana with markers of chronic lung disease in people living with HIV.

HIV medicine

Wenger DS, Triplette M, Shahrir S, Akgun KM, Wongtrakool C, Brown ST, Kim JW, Soo Hoo GW, Rodriguez-Barradas MC, Huang L, Feemster LC, Zifodya J, Crothers K

Distinct lung microbiota associate with HIV-associated chronic lung disease in children.

Scientific reports

Bhadriraju S, Fadrosh DW, Shenoy MK, Lin DL, Lynch KV, McCauley K, Ferrand RA, Majonga ED, McHugh G, Huang L, Lynch SV, Metcalfe JZ

Sonographic B-lines, Fluid Resuscitation, and Hypoxemia in Malawian Patients with Suspected Sepsis.

American journal of respiratory and critical care medicine

Wang RJ, Katha G, Phiri M, Delbridge P, Gordon SB, Calfee CS, Huang L, Rylance J

Validation for using electronic health records to identify community acquired pneumonia hospitalization among people with and without HIV.

Pneumonia (Nathan Qld.)

Rodriguez-Barradas MC, McGinnis KA, Akgün K, Tate JP, Brown ST, Butt AA, Fine M, Goetz MB, Graber CJ, Huang L, Rimland D, Justice A, Crothers K

HIV X4 Variants Increase Arachidonate 5-Lipoxygenase in the Pulmonary Microenvironment and are associated with Pulmonary Arterial Hypertension.

Scientific reports

Almodovar S, Wade BE, Porter KM, Smith JM, Lopez-Astacio RA, Bijli K, Kang BY, Cribbs SK, Guidot DM, Molehin D, McNair BK, Pumarejo-Gomez L, Perez Hernandez J, Salazar EA, Martinez EG, Huang L, Kessing CF, Suarez-Martinez EB, Pruitt K, Hsue PY, Tyor WR, Flores SC, Sutliff RL

Association Between Inflammatory Pathways and Phenotypes of Pulmonary Dysfunction Using Cluster Analysis in Persons Living With HIV and HIV-Uninfected Individuals.

Journal of acquired immune deficiency syndromes (1999)

Qin S, Vodovotz L, Zamora R, Fitzpatrick M, Kessinger C, Kingsley L, McMahon D, DeSensi R, Leader JK, Crothers K, Huang L, Morris A, Nouraie M

Pneumoproteins are associated with pulmonary function in HIV-infected persons.

PloS one

Jeon D, Chang EG, McGing M, Hartman-Filson M, Sommers M, Lewis E, Balmes JR, Moisi D, Lederman MM, Madsen KA, Woodruff PG, Hunt PW, Huang L

Global Health-related Training Opportunities. A National Survey of Pulmonary and Critical Care Medicine Fellowship Programs.

Annals of the American Thoracic Society

North CM, Attia EF, Rudd KE, Siddharthan T, Papali A, Çoruh B, Carter EJ, Christiani DC, Richards JB, Huang L, Engelberg R, Checkley W, West TE

Association between common telomere length genetic variants and telomere length in an African population and impacts of HIV and TB.

Journal of human genetics

Wang S, Chang E, Byanyima P, Huang P, Sanyu I, Musisi E, Sessolo A, Davis JL, Worodria W, Huang L, Lin J

HIV infection is associated with elevated biomarkers of immune activation in Ugandan adults with pneumonia.

PloS one

Wang RJ, Moore J, Moisi D, Chang EG, Byanyima P, Kaswabuli S, Musisi E, Sanyu I, Sessolo A, Lalitha R, Worodria W, Davis JL, Crothers K, Lin J, Lederman MM, Hunt PW, Huang L

HIV infection is an independent risk factor for decreased 6-minute walk test distance.

PloS one

Robertson TE, Nouraie M, Qin S, Crothers KA, Kessinger CJ, McMahon D, Chandra D, Kingsley LA, Greenblatt RM, Huang L, Fitzpatrick ME, Morris A

Gut microbiota in HIV-pneumonia patients is related to peripheral CD4 counts, lung microbiota, and in vitro macrophage dysfunction.

Microbiome

Shenoy MK, Fadrosh DW, Lin DL, Worodria W, Byanyima P, Musisi E, Kaswabuli S, Zawedde J, Sanyu I, Chang E, Fong S, McCauley K, Davis JL, Huang L, Lynch SV

Medical Intensive Care Unit Admission Among Patients With and Without HIV, Hepatitis C Virus, and Alcohol-Related Diagnoses in the United States: A National, Retrospective Cohort Study, 1997-2014.

Journal of acquired immune deficiency syndromes (1999)

Rentsch CT, Tate JP, Steel T, Butt AA, Gibert CL, Huang L, Pisani M, Soo Hoo GW, Crystal S, Rodriguez-Barradas MC, Brown ST, Freiberg MS, Graber CJ, Kim JW, Rimland D, Justice AC, Fiellin DA, Crothers KA, Akgün KM

Predictors of Mortality Among Hospitalized Patients With Lower Respiratory Tract Infections in a High HIV Burden Setting.

Journal of acquired immune deficiency syndromes (1999)

Worodria W, Chang E, Andama A, Sanyu I, Byanyima P, Musisi E, Kaswabuli S, Zawedde J, Ayakaka I, Sessolo A, Lalitha R, Davis JL, Huang L

Factors Associated With Progression of Lung Function Abnormalities in HIV-Infected Individuals.

Journal of acquired immune deficiency syndromes (1999)

Li Y, Nouraie SM, Kessinger C, Weinman R, Huang L, Greenblatt RM, Kleerup E, Kingsley L, McMahon D, Fitzpatrick M, Morris A

Diagnostic performance of blood inflammatory markers for tuberculosis screening in people living with HIV.

PloS one

Farr K, Ravindran R, Strnad L, Chang E, Chaisson LH, Yoon C, Worodria W, Andama A, Ayakaka I, Bbosa Nalwanga P, Byanyima P, Kalema N, Kaswabuli S, Katagira W, Aman KD, Musisi E, Tumwine NW, Sanyu I, Ssebunya R, Davis JL, Huang L, Khan IH, Cattamanchi A

Tropheryma whipplei colonization in HIV-infected individuals is not associated with lung function or inflammation.

PloS one

Qin S, Clausen E, Nouraie SM, Kingsley L, McMahon D, Kleerup E, Huang L, Ghedin E, Greenblatt RM, Morris A

Effect of anti-retroviral therapy on oxidative stress in hospitalized HIV-infected adults with and without TB.

African health sciences

Musisi E, Matovu DK, Bukenya A, Kaswabuli S, Zawedde J, Andama A, Byanyima P, Sanyu I, Sessolo A, Seremba E, Davis JL, Worodria W, Huang L, Walter ND, Mayanja-Kizza H

Does discovery of differentially culturable M tuberculosis really demand a new treatment paradigm? Longitudinal analysis of DNA clearance from sputum.

BMC infectious diseases

Walter ND, Moore CM, Kayigire XA, Dide-Agossou C, Worodria W, Huang L, Everett CK, Schoolnik GS, Nahid P, Davis JL

Measuring associations between the microbiota and repeated measures of continuous clinical variables using a lasso-penalized generalized linear mixed model.

BioData mining

Tipton L, Cuenco KT, Huang L, Greenblatt RM, Kleerup E, Sciurba F, Duncan SR, Donahoe MP, Morris A, Ghedin E

Decreased Lung Function and All-Cause Mortality in HIV-infected Individuals.

Annals of the American Thoracic Society

Gingo MR, Nouraie M, Kessinger CJ, Greenblatt RM, Huang L, Kleerup EC, Kingsley L, McMahon DK, Morris A

Fungi stabilize connectivity in the lung and skin microbial ecosystems.

Microbiome

Tipton L, Müller CL, Kurtz ZD, Huang L, Kleerup E, Morris A, Bonneau R, Ghedin E

Unusual Radiographic Presentation of Pneumocystis Pneumonia in a Patient with AIDS.

Case reports in infectious diseases

Block BL, Mehta T, Ortiz GM, Ferris SP, Vu TH, Huang L, Cattamanchi A

Point-of-care C-reactive protein-based tuberculosis screening for people living with HIV: a diagnostic accuracy study.

The Lancet. Infectious diseases

Yoon C, Semitala FC, Atuhumuza E, Katende J, Mwebe S, Asege L, Armstrong DT, Andama AO, Dowdy DW, Davis JL, Huang L, Kamya M, Cattamanchi A

Evaluation of antibody responses to panels of M. tuberculosis antigens as a screening tool for active tuberculosis in Uganda.

PloS one

Shete PB, Ravindran R, Chang E, Worodria W, Chaisson LH, Andama A, Davis JL, Luciw PA, Huang L, Khan IH, Cattamanchi A

Effects of clinical and environmental factors on bronchoalveolar antibody responses to Pneumocystis jirovecii: A prospective cohort study of HIV+ patients.

PloS one

Blount RJ, Daly KR, Fong S, Chang E, Grieco K, Greene M, Stone S, Balmes J, Miller RF, Walzer PD, Huang L

Sputum quality and diagnostic performance of GeneXpert MTB/RIF among smear-negative adults with presumed tuberculosis in Uganda.

PloS one

Meyer AJ, Atuheire C, Worodria W, Kizito S, Katamba A, Sanyu I, Andama A, Ayakaka I, Cattamanchi A, Bwanga F, Huang L, Davis JL

Investigation of OMNIgene·SPUTUM performance in delayed tuberculosis testing by smear, culture, and Xpert MTB/RIF assays in Uganda.

Journal of epidemiology and global health

Kelly-Cirino CD, Musisi E, Byanyima P, Kaswabuli S, Andama A, Sessolo A, Sanyu I, Zawedde J, Curry PS, Huang L

Use of rosuvastatin in HIV-associated chronic obstructive pulmonary disease.

AIDS (London, England)

Morris A, Fitzpatrick M, Bertolet M, Qin S, Kingsley L, Leo N, Kessinger C, Michael H, Mcmahon D, Weinman R, Stone S, Leader JK, Kleerup E, Huang L, Wisniewski SR

A Low Peripheral Blood CD4/CD8 Ratio Is Associated with Pulmonary Emphysema in HIV.

PloS one

Triplette M, Attia EF, Akgün KM, Soo Hoo GW, Freiberg MS, Butt AA, Wongtrakool C, Goetz MB, Brown ST, Graber CJ, Huang L, Crothers K

High Prevalence of Pneumocystis jirovecii Dihydropteroate Synthase Gene Mutations in Patients with a First Episode of Pneumocystis Pneumonia in Santiago, Chile, and Clinical Response to Trimethoprim-Sulfamethoxazole Therapy.

Antimicrobial agents and chemotherapy

Ponce CA, Chabé M, George C, Cárdenas A, Durán L, Guerrero J, Bustamante R, Matos O, Huang L, Miller RF, Vargas SL

Immune Response and Mortality Risk Relate to Distinct Lung Microbiomes in Patients with HIV and Pneumonia.

American journal of respiratory and critical care medicine

Shenoy MK, Iwai S, Lin DL, Worodria W, Ayakaka I, Byanyima P, Kaswabuli S, Fong S, Stone S, Chang E, Davis JL, Faruqi AA, Segal MR, Huang L, Lynch SV

Predictors and short-term outcomes of recurrent pulmonary tuberculosis, Uganda: a cohort study.

South African respiratory journal

Kalema N, Lindan C, Glidden D, Yoo SD, Katamba A, Alfred A, Katagira W, Byanyima P, Musisi E, Kaswabuli S, Ingvar S, Zawedde J, Yoon C, Ayakaka I, Davis JL, Huang L, Worodria W, Cattamanchi A

HIV Infection Is Associated with Shortened Telomere Length in Ugandans with Suspected Tuberculosis.

PloS one

Auld E, Lin J, Chang E, Byanyima P, Ayakaka I, Musisi E, Worodria W, Davis JL, Segal M, Blackburn E, Huang L

Adaptation of Mycobacterium tuberculosis to Impaired Host Immunity in HIV-Infected Patients.

The Journal of infectious diseases

Walter ND, de Jong BC, Garcia BJ, Dolganov GM, Worodria W, Byanyima P, Musisi E, Huang L, Chan ED, Van TT, Antonio M, Ayorinde A, Kato-Maeda M, Nahid P, Leung AM, Yen A, Fingerlin TE, Kechris K, Strong M, Voskuil MI, Davis JL, Schoolnik GK

Empiric TB Treatment of Severely Ill Patients With HIV and Presumed Pulmonary TB Improves Survival.

Journal of acquired immune deficiency syndromes (1999)

Katagira W, Walter ND, Den Boon S, Kalema N, Ayakaka I, Vittinghoff E, Worodria W, Cattamanchi A, Huang L, Davis JL

Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype.

Nature microbiology

Segal LN, Clemente JC, Tsay JC, Koralov SB, Keller BC, Wu BG, Li Y, Shen N, Ghedin E, Morris A, Diaz P, Huang L, Wikoff WR, Ubeda C, Artacho A, Rom WN, Sterman DH, Collman RG, Blaser MJ, Weiden MD

Risk Factors Associated With Quantitative Evidence of Lung Emphysema and Fibrosis in an HIV-Infected Cohort.

Journal of acquired immune deficiency syndromes (1999)

Leader JK, Crothers K, Huang L, King MA, Morris A, Thompson BW, Flores SC, Drummond MB, Rom WN, Diaz PT

Multicentre study highlighting clinical relevance of new high-throughput methodologies in molecular epidemiology of Pneumocystis jirovecii pneumonia.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Esteves F, de Sousa B, Calderón EJ, Huang L, Badura R, Maltez F, Bassat Q, de Armas Y, Antunes F, Matos O

Evaluation and Diagnosis of HIV-Associated Lung Disease.

Seminars in respiratory and critical care medicine

Maximous S, Huang L, Morris A

Obstructive Lung Diseases in HIV: A Clinical Review and Identification of Key Future Research Needs.

Seminars in respiratory and critical care medicine

Drummond MB, Kunisaki KM, Huang L

Pulmonary Complications of HIV Infection.

Seminars in respiratory and critical care medicine

Huang L, Morris A, Crothers K

Correlation of the lung microbiota with metabolic profiles in bronchoalveolar lavage fluid in HIV infection.

Microbiome

Cribbs SK, Uppal K, Li S, Jones DP, Huang L, Tipton L, Fitch A, Greenblatt RM, Kingsley L, Guidot DM, Ghedin E, Morris A

Multicenter Comparison of Lung and Oral Microbiomes of HIV-infected and HIV-uninfected Individuals.

American journal of respiratory and critical care medicine

Beck JM, Schloss PD, Venkataraman A, Twigg H, Jablonski KA, Bushman FD, Campbell TB, Charlson ES, Collman RG, Crothers K, Curtis JL, Drews KL, Flores SC, Fontenot AP, Foulkes MA, Frank I, Ghedin E, Huang L, Lynch SV, Morris A, Palmer BE, Schmidt TM, Sodergren E, Weinstock GM, Young VB

Association of COPD With Risk for Pulmonary Infections Requiring Hospitalization in HIV-Infected Veterans.

Journal of acquired immune deficiency syndromes (1999)

Attia EF, McGinnis KA, Feemster LC, Akgün KM, Butt AA, Graber CJ, Fine MJ, Goetz MB, Rodriguez-Barradas MC, Pisani MA, Tindle HA, Brown ST, Soo Hoo GW, Rimland D, Gibert CL, Huang L, Freiberg MS, Hough CL, Crothers K

Factors associated with abnormal spirometry among HIV-infected individuals.

AIDS (London, England)

Drummond MB, Huang L, Diaz PT, Kirk GD, Kleerup EC, Morris A, Rom W, Weiden MD, Zhao E, Thompson B, Crothers K

Use of Oropharyngeal Washes to Diagnose and Genotype Pneumocystis jirovecii.

Open forum infectious diseases

Juliano JJ, Barnett E, Parobek CM, Taylor SM, Meshnick SR, Stone S, Chang E, Fong S, Huang L

A Clinical Predictor Score for 30-Day Mortality among HIV-Infected Adults Hospitalized with Pneumonia in Uganda.

PloS one

Koss CA, Jarlsberg LG, den Boon S, Cattamanchi A, Davis JL, Worodria W, Ayakaka I, Sanyu I, Huang L

Impact of mycobacterial culture among HIV-infected adults with presumed TB in Uganda: a prospective cohort study.

Public health action

Semitala FC, Chaisson LH, den Boon S, Walter N, Cattamanchi A, Awor M, Katende J, Huang L, Joloba M, Albert H, Kamya MR, Davis JL

Topographic diversity of the respiratory tract mycobiome and alteration in HIV and lung disease.

American journal of respiratory and critical care medicine

Cui L, Lucht L, Tipton L, Rogers MB, Fitch A, Kessinger C, Camp D, Kingsley L, Leo N, Greenblatt RM, Fong S, Stone S, Dermand JC, Kleerup EC, Huang L, Morris A, Ghedin E

Transcriptional Adaptation of Drug-tolerant Mycobacterium tuberculosis During Treatment of Human Tuberculosis.

The Journal of infectious diseases

Walter ND, Dolganov GM, Garcia BJ, Worodria W, Andama A, Musisi E, Ayakaka I, Van TT, Voskuil MI, de Jong BC, Davidson RM, Fingerlin TE, Kechris K, Palmer C, Nahid P, Daley CL, Geraci M, Huang L, Cattamanchi A, Strong M, Schoolnik GK, Davis JL

Pulmonary Function in HIV-Infected Recreational Drug Users in the Era of Anti-Retroviral Therapy.

Journal of AIDS & clinical research

Simonetti JA, Gingo MR, Kingsley L, Kessinger C, Lucht L, Balasubramani G, Leader JK, Huang L, Greenblatt RM, Dermand J, Kleerup EC, Morris A

The microbiome and the lung.

Annals of the American Thoracic Society

Cui L, Morris A, Huang L, Beck JM, Twigg HL, von Mutius E, Ghedin E

Low tidal volume ventilation is associated with reduced mortality in HIV-infected patients with acute lung injury.

Thorax

Davis JL, Morris A, Kallet RH, Powell K, Chi AS, Bensley M, Luce JM, Huang L

A prospective, blinded study of quantitative touch-down polymerase chain reaction using oral-wash samples for diagnosis of Pneumocystis pneumonia in HIV-infected patients.

The Journal of infectious diseases

Larsen HH, Huang L, Kovacs JA, Crothers K, Silcott VA, Morris A, Turner JR, Beard CB, Masur H, Fischer SH

Dihydropteroate synthase gene mutations in Pneumocystis and sulfa resistance.

Emerging infectious diseases

Huang L, Crothers K, Atzori C, Benfield T, Miller R, Rabodonirina M, Helweg-Larsen J

Pulmonary symptoms and diagnoses are associated with HIV in the MACS and WIHS cohorts.

BMC pulmonary medicine

Gingo MR, Balasubramani GK, Rice TB, Kingsley L, Kleerup EC, Detels R, Seaberg EC, Greenblatt RM, Holman S, Huang L, Sutton SH, Bertolet M, Morris A

The lung microbiome of Ugandan HIV-infected pneumonia patients is compositionally and functionally distinct from that of San Franciscan patients.

PloS one

Iwai S, Huang D, Fong S, Jarlsberg LG, Worodria W, Yoo S, Cattamanchi A, Davis JL, Kaswabuli S, Segal M, Huang L, Lynch SV

Association of chronic cough and pulmonary function with 6-minute walk test performance in HIV infection.

Journal of acquired immune deficiency syndromes (1999)

Campo M, Oursler KK, Huang L, Goetz MB, Rimland D, Hoo GS, Brown ST, Rodriguez-Barradas MC, Au D, Akgün KM, Shahrir S, Crothers K

Point-of-care C-reactive protein testing to facilitate implementation of isoniazid preventive therapy for people living with HIV.

Journal of acquired immune deficiency syndromes (1999)

Yoon C, Davis JL, Huang L, Muzoora C, Byakwaga H, Scibetta C, Bangsberg DR, Nahid P, Semitala FC, Hunt PW, Martin JN, Cattamanchi A

Multilocus microsatellite genotyping array for investigation of genetic epidemiology of Pneumocystis jirovecii.

Journal of clinical microbiology

Parobek CM, Jiang LY, Patel JC, Alvarez-Martínez MJ, Miro JM, Worodria W, Andama A, Fong S, Huang L, Meshnick SR, Taylor SM, Juliano JJ

Procalcitonin predicts mortality in HIV-infected Ugandan adults with lower respiratory tract infections.

Respirology (Carlton, Vic.)

Tokman S, Barnett CF, Jarlsberg LG, Taub PR, den Boon S, Davis JL, Cattamanchi A, Worodria W, Maisel A, Huang L

HIV infection is associated with diffusing capacity impairment in women.

Journal of acquired immune deficiency syndromes (1999)

Fitzpatrick ME, Gingo MR, Kessinger C, Lucht L, Kleerup E, Greenblatt RM, Claman D, Ponath C, Fong S, Huang L, Morris A

HIV infection is associated with reduced pulmonary diffusing capacity.

Journal of acquired immune deficiency syndromes (1999)

Crothers K, McGinnis K, Kleerup E, Wongtrakool C, Hoo GS, Kim J, Sharafkhaneh A, Huang L, Luo Z, Thompson B, Diaz P, Kirk GD, Rom W, Detels R, Kingsley L, Morris A

Antibody responses against Pneumocystis jirovecii in health care workers over time.

Emerging infectious diseases

Fong S, Daly KR, Tipirneni R, Jarlsberg LG, Djawe K, Koch JV, Swartzman A, Roth B, Walzer PD, Huang L

Use of bronchoalveolar lavage to assess the respiratory microbiome: signal in the noise.

The Lancet. Respiratory medicine

Twigg HL, Morris A, Ghedin E, Curtis JL, Huffnagle GB, Crothers K, Campbell TB, Flores SC, Fontenot AP, Beck JM, Huang L, Lynch S, Knox KS, Weinstock G

Medical ICU admission diagnoses and outcomes in human immunodeficiency virus-infected and virus-uninfected veterans in the combination antiretroviral era.

Critical care medicine

Akgün KM, Tate JP, Pisani M, Fried T, Butt AA, Gibert CL, Huang L, Rodriguez-Barradas MC, Rimland D, Justice AC, Crothers K

Prevalence and outcomes of cryptococcal antigenemia in HIV-seropositive patients hospitalized for suspected tuberculosis in Uganda.

Journal of acquired immune deficiency syndromes (1999)

Andama AO, den Boon S, Meya D, Cattamanchi A, Worodria W, Davis JL, Walter ND, Yoo SD, Kalema N, Haller B, Huang L

Comparison of the respiratory microbiome in healthy nonsmokers and smokers.

American journal of respiratory and critical care medicine

Morris A, Beck JM, Schloss PD, Campbell TB, Crothers K, Curtis JL, Flores SC, Fontenot AP, Ghedin E, Huang L, Jablonski K, Kleerup E, Lynch SV, Sodergren E, Twigg H, Young VB, Bassis CM, Venkataraman A, Schmidt TM, Weinstock GM

Widespread colonization of the lung by Tropheryma whipplei in HIV infection.

American journal of respiratory and critical care medicine

Lozupone C, Cota-Gomez A, Palmer BE, Linderman DJ, Charlson ES, Sodergren E, Mitreva M, Abubucker S, Martin J, Yao G, Campbell TB, Flores SC, Ackerman G, Stombaugh J, Ursell L, Beck JM, Curtis JL, Young VB, Lynch SV, Huang L, Weinstock GM, Knox KS, Twigg H, Morris A, Ghedin E, Bushman FD, Collman RG, Knight R, Fontenot AP

Characteristics of Drug-Susceptible and Drug-Resistant Staphylococcus aureus Pneumonia in Patients with HIV.

Epidemiology (Sunnyvale, Calif.)

Everett CK, Subramanian A, Jarisberg LG, Fei M, Huang L

Evaluation of respiratory disease.

Clinics in chest medicine

Tokman S, Huang L

Pneumocystis pneumonia associated with human immunodeficiency virus.

Clinics in chest medicine

Miller RF, Huang L, Walzer PD

Mobile digital fluorescence microscopy for diagnosis of tuberculosis.

Journal of clinical microbiology

Tapley A, Switz N, Reber C, Davis JL, Miller C, Matovu JB, Worodria W, Huang L, Fletcher DA, Cattamanchi A

The impact of HAART on the respiratory complications of HIV infection: longitudinal trends in the MACS and WIHS cohorts.

PloS one

Gingo MR, Balasubramani GK, Kingsley L, Rinaldo CR, Alden CB, Detels R, Greenblatt RM, Hessol NA, Holman S, Huang L, Kleerup EC, Phair J, Sutton SH, Seaberg EC, Margolick JB, Wisniewski SR, Morris A

Dihydropteroate synthase mutations in Pneumocystis pneumonia: impact of applying different definitions of prophylaxis, mortality endpoints and mutant in a single cohort.

Medical mycology

Yoon C, Subramanian A, Chi A, Crothers K, Meshnick SR, Taylor SM, Beard CB, Jarlsberg LG, Lawrence GG, Avery M, Swartzman A, Fong S, Roth B, Huang L

A double-edged sword.

Journal of hospital medicine

Baxi S, Platts-Mills J, Dhruva S, Huang L, Hanks D, Dhaliwal G

Risk factors for hospitalization and medical intensive care unit (MICU) admission among HIV-infected Veterans.

Journal of acquired immune deficiency syndromes (1999)

Akgün KM, Gordon K, Pisani M, Fried T, McGinnis KA, Tate JP, Butt AA, Gibert CL, Huang L, Rodriguez-Barradas MC, Rimland D, Justice AC, Crothers K

Serologic responses to recombinant Pneumocystis jirovecii major surface glycoprotein among Ugandan patients with respiratory symptoms.

PloS one

Blount RJ, Jarlsberg LG, Daly KR, Worodria W, Davis JL, Cattamanchi A, Djawe K, Andama A, Koch J, Walzer PD, Huang L

Low prevalence of Pneumocystis pneumonia (PCP) but high prevalence of pneumocystis dihydropteroate synthase (dhps) gene mutations in HIV-infected persons in Uganda.

PloS one

Taylor SM, Meshnick SR, Worodria W, Andama A, Cattamanchi A, Davis JL, Yoo SD, Byanyima P, Kaswabuli S, Goodman CD, Huang L

Impact of Xpert MTB/RIF testing on tuberculosis management and outcomes in hospitalized patients in Uganda.

PloS one

Yoon C, Cattamanchi A, Davis JL, Worodria W, den Boon S, Kalema N, Katagira W, Kaswabuli S, Miller C, Andama A, Albert H, Nabeta P, Gray C, Ayakaka I, Huang L

Environmental risk factors for Pneumocystis pneumonia hospitalizations in HIV patients.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Djawe K, Levin L, Swartzman A, Fong S, Roth B, Subramanian A, Grieco K, Jarlsberg L, Miller RF, Huang L, Walzer PD

Evaluation of in-house PCR for diagnosis of smear-negative pulmonary tuberculosis in Kampala, Uganda.

BMC research notes

Nakiyingi L, Kateete DP, Ocama P, Worodria W, Sempa JB, Asiimwe BB, Katabazi FA, Katamba A, Huang L, Joloba ML, Mayanja-Kizza H

Oral antimicrobial rinse to reduce mycobacterial culture contamination among tuberculosis suspects in Uganda: a prospective study.

PloS one

Kalema N, Boon SD, Cattamanchi A, Davis JL, Andama A, Katagira W, Everett C, Walter N, Byanyima P, Kaswabuli S, Worodria W, Huang L

Oral and airway microbiota in HIV-infected pneumonia patients.

Journal of clinical microbiology

Iwai S, Fei M, Huang D, Fong S, Subramanian A, Grieco K, Lynch SV, Huang L

Bronchoalveolar lavage enzyme-linked immunospot for diagnosis of smear-negative tuberculosis in HIV-infected patients.

PloS one

Cattamanchi A, Ssewenyana I, Nabatanzi R, Miller CR, Den Boon S, Davis JL, Andama A, Worodria W, Yoo SD, Cao H, Huang L

A mentor development program for clinical translational science faculty leads to sustained, improved confidence in mentoring skills.

Clinical and translational science

Feldman MD, Steinauer JE, Khalili M, Huang L, Kahn JS, Lee KA, Creasman J, Brown JS

Low prevalence of Pneumocystis jirovecii lung colonization in Ugandan HIV-infected patients hospitalized with non-Pneumocystis pneumonia.

Diagnostic microbiology and infectious disease

Taylor SM, Meshnick SR, Worodria W, Andama A, Davis JL, Cattamanchi A, den Boon S, Yoo SD, Goodman CD, Huang L

Interferon-? release assays for active pulmonary tuberculosis diagnosis in adults in low- and middle-income countries: systematic review and meta-analysis.

The Journal of infectious diseases

Metcalfe JZ, Everett CK, Steingart KR, Cattamanchi A, Huang L, Hopewell PC, Pai M

The role of speciation in positive Lowenstein-Jensen culture isolates from a high tuberculosis burden country.

PloS one

Worodria W, Anderson J, Cattamanchi A, Davis JL, den Boon S, Andama A, Yoo SD, Joloba M, Huang L, Kato-Maeda M

Chest radiographic findings of pulmonary tuberculosis in severely immunocompromised patients with the human immunodeficiency virus.

The British journal of radiology

Kisembo HN, Boon SD, Davis JL, Okello R, Worodria W, Cattamanchi A, Huang L, Kawooya MG

Clinical significance of normal chest radiographs among HIV-seropositive patients with suspected tuberculosis in Uganda.

Respirology (Carlton, Vic.)

Yoo SD, Cattamanchi A, Den Boon S, Worodria W, Kisembo H, Huang L, Davis JL

Critical illness in HIV-infected patients in the era of combination antiretroviral therapy.

Proceedings of the American Thoracic Society

Akgün KM, Huang L, Morris A, Justice AC, Pisani M, Crothers K

HIV and chronic obstructive pulmonary disease: is it worse and why?

Proceedings of the American Thoracic Society

Morris A, George MP, Crothers K, Huang L, Lucht L, Kessinger C, Kleerup EC

HIV-associated Pneumocystis pneumonia.

Proceedings of the American Thoracic Society

Huang L, Cattamanchi A, Davis JL, den Boon S, Kovacs J, Meshnick S, Miller RF, Walzer PD, Worodria W, Masur H

HIV-associated lung infections and complications in the era of combination antiretroviral therapy.

Proceedings of the American Thoracic Society

Crothers K, Thompson BW, Burkhardt K, Morris A, Flores SC, Diaz PT, Chaisson RE, Kirk GD, Rom WN, Huang L

Pandemic (H1N1) 2009 and HIV Infection.

Emerging infectious diseases

Dhanireddy S, Harrington RD, Crane HM, Gingo MR, Morris A, Huang L, Crothers K

Pathogenesis of HIV-associated pulmonary hypertension: potential role of HIV-1 Nef.

Proceedings of the American Thoracic Society

Almodovar S, Hsue PY, Morelli J, Huang L, Flores SC

Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study.

Lancet (London, England)

Boehme CC, Nicol MP, Nabeta P, Michael JS, Gotuzzo E, Tahirli R, Gler MT, Blakemore R, Worodria W, Gray C, Huang L, Caceres T, Mehdiyev R, Raymond L, Whitelaw A, Sagadevan K, Alexander H, Albert H, Cobelens F, Cox H, Alland D, Perkins MD

Evaluating tuberculosis case detection via real-time monitoring of tuberculosis diagnostic services.

American journal of respiratory and critical care medicine

Davis J, Katamba A, Vasquez J, Crawford E, Sserwanga A, Kakeeto S, Kizito F, Dorsey G, den Boon S, Vittinghoff E, Huang L, Adatu F, Kamya MR, Hopewell PC, Cattamanchi A

An official ATS workshop report: Emerging issues and current controversies in HIV-associated pulmonary diseases.

Proceedings of the American Thoracic Society

Morris A, Crothers K, Beck JM, Huang L

Interferon-gamma release assays for the diagnosis of latent tuberculosis infection in HIV-infected individuals: a systematic review and meta-analysis.

Journal of acquired immune deficiency syndromes (1999)

Cattamanchi A, Smith R, Steingart KR, Metcalfe JZ, Date A, Coleman C, Marston BJ, Huang L, Hopewell PC, Pai M

Nucleic acid amplification tests for diagnosis of smear-negative TB in a high HIV-prevalence setting: a prospective cohort study.

PloS one

Davis JL, Huang L, Worodria W, Masur H, Cattamanchi A, Huber C, Miller C, Conville PS, Murray P, Kovacs JA

Serum antibody levels to the Pneumocystis jirovecii major surface glycoprotein in the diagnosis of P. jirovecii pneumonia in HIV+ patients.

PloS one

Djawe K, Huang L, Daly KR, Levin L, Koch J, Schwartzman A, Fong S, Roth B, Subramanian A, Grieco K, Jarlsberg L, Walzer PD

Causes of early mortality in HIV-infected TB suspects in an East African referral hospital.

Journal of acquired immune deficiency syndromes (1999)

Kyeyune R, den Boon S, Cattamanchi A, Davis JL, Worodria W, Yoo SD, Huang L

HIV infection and risk for incident pulmonary diseases in the combination antiretroviral therapy era.

American journal of respiratory and critical care medicine

Crothers K, Huang L, Goulet JL, Goetz MB, Brown ST, Rodriguez-Barradas MC, Oursler KK, Rimland D, Gibert CL, Butt AA, Justice AC

Integrated strategies to optimize sputum smear microscopy: a prospective observational study.

American journal of respiratory and critical care medicine

Cattamanchi A, Huang L, Worodria W, den Boon S, Kalema N, Katagira W, Byanyima P, Yoo S, Matovu J, Hopewell PC, Davis JL

Bronchoscopy is useful for diagnosing smear-negative tuberculosis in HIV-infected patients.

The European respiratory journal

Worodria W, Davis JL, Cattamanchi A, Andama A, den Boon S, Yoo SD, Hopewell PC, Huang L

The prevalence and clinical course of HIV-associated pulmonary cryptococcosis in Uganda.

Journal of acquired immune deficiency syndromes (1999)

Deok-jong Yoo S, Worodria W, Davis JL, Cattamanchi A, den Boon S, Kyeyune R, Kisembo H, Huang L

Respiratory emergencies in HIV-infected persons.

Emergency medicine clinics of North America

Everett CK, Fei MW, Huang L

Does bleach processing increase the accuracy of sputum smear microscopy for diagnosing pulmonary tuberculosis?

Journal of clinical microbiology

Cattamanchi A, Davis JL, Pai M, Huang L, Hopewell PC, Steingart KR

Clinical and radiographic factors do not accurately diagnose smear-negative tuberculosis in HIV-infected inpatients in Uganda: a cross-sectional study.

PloS one

Davis JL, Worodria W, Kisembo H, Metcalfe JZ, Cattamanchi A, Kawooya M, Kyeyune R, den Boon S, Powell K, Okello R, Yoo S, Huang L

Role of interferon-gamma release assays in the diagnosis of pulmonary tuberculosis in patients with advanced HIV infection.

BMC infectious diseases

Cattamanchi A, Ssewenyana I, Davis JL, Huang L, Worodria W, den Boon S, Yoo S, Andama A, Hopewell PC, Cao H

Pneumocystis infection: unraveling the colonization-to-disease shift.

Expert review of anti-infective therapy

Calderon EJ, Dei-Cas E

Restriction fragment length polymorphism typing demonstrates substantial diversity among Pneumocystis jirovecii isolates.

The Journal of infectious diseases

Ripamonti C, Orenstein A, Kutty G, Huang L, Schuhegger R, Sing A, Fantoni G, Atzori C, Vinton C, Huber C, Conville PS, Kovacs JA

Healthcare worker occupation and immune response to Pneumocystis jirovecii.

Emerging infectious diseases

Tipirneni R, Daly KR, Jarlsberg LG, Koch JV, Swartzman A, Roth BM, Walzer PD, Huang L

Sensitivity and specificity of fluorescence microscopy for diagnosing pulmonary tuberculosis in a high HIV prevalence setting.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

Cattamanchi A, Davis JL, Worodria W, den Boon S, Yoo S, Matovu J, Kiidha J, Nankya F, Kyeyune R, Byanyima P, Andama A, Joloba M, Osmond DH, Hopewell PC, Huang L

The ART of caring for patients with HIV infection in the ICU.

Intensive care medicine

Powell K, Huang L

Respiratory symptoms and airway obstruction in HIV-infected subjects in the HAART era.

PloS one

George MP, Kannass M, Huang L, Sciurba FC, Morris A

Modified Giemsa method for confirmation of Pneumocystis pneumonia in low-income countries.

BMJ case reports

Andama AO, Cattamanchi A, Davis JL, den Boon S, Worodria W, Huang L

Training the next generation of research mentors: the University of California, San Francisco, Clinical & Translational Science Institute Mentor Development Program.

Clinical and translational science

Feldman MD, Huang L, Guglielmo BJ, Jordan R, Kahn J, Creasman JM, Wiener-Kronish JP, Lee KA, Tehrani A, Yaffe K, Brown JS

Sensitivity of direct versus concentrated sputum smear microscopy in HIV-infected patients suspected of having pulmonary tuberculosis.

BMC infectious diseases

Cattamanchi A, Dowdy DW, Davis JL, Worodria W, Yoo S, Joloba M, Matovu J, Hopewell PC, Huang L

HIV-associated opportunistic pneumonias.

Respirology (Carlton, Vic.)

Huang L, Crothers K

Nonadherence to primary prophylaxis against Pneumocystis jirovecii pneumonia.

PloS one

Heffelfinger JD, Voetsch AC, Nakamura GV, Sullivan PS, McNaghten AD, Huang L

High sensitivity and specificity of acid-fast microscopy for diagnosis of pulmonary tuberculosis in an African population with a high prevalence of human immunodeficiency virus.

Journal of clinical microbiology

Shea YR, Davis JL, Huang L, Kovacs JA, Masur H, Mulindwa F, Opus S, Chow Y, Murray PR

Polymerase chain reaction of secA1 on sputum or oral wash samples for the diagnosis of pulmonary tuberculosis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Davis JL, Huang L, Kovacs JA, Masur H, Murray P, Havlir DV, Worodria WO, Charlebois ED, Srikantiah P, Cattamanchi A, Huber C, Shea YR, Chow Y, Fischer SH

Performance of modified universal sample processing method in a field study in Uganda.

Journal of clinical microbiology

Chakravorty S, Tyagi JS, Cattamanchi A, Davis JL, Worodria W, Yoo S, Huang L

Severity and outcomes of Pneumocystis pneumonia in patients newly diagnosed with HIV infection: an observational cohort study.

Scandinavian journal of infectious diseases

Fei MW, Sant CA, Kim EJ, Swartzman A, Davis JL, Jarlsberg LG, Huang L

Poor performance of universal sample processing method for diagnosis of pulmonary tuberculosis by smear microscopy and culture in Uganda.

Journal of clinical microbiology

Cattamanchi A, Davis JL, Worodria W, Yoo S, Matovu J, Kiidha J, Nankya F, Kyeyune R, Andama A, Joloba M, Osmond D, Hopewell P, Huang L

A hydrophilic-interaction chromatography tandem mass spectrometry method for quantitation of serum s-adenosylmethionine in patients infected with human immunodeficiency virus.

Clinica chimica acta; international journal of clinical chemistry

Wang P, Huang L, Davis JL, Swartzman A, Roth B, Stone J, Wu AH

Role of HIV and human herpesvirus-8 infection in pulmonary arterial hypertension.

AIDS (London, England)

Hsue PY, Deeks SG, Farah HH, Palav S, Ahmed SY, Schnell A, Ellman AB, Huang L, Dollard SC, Martin JN

Respiratory infection complicating HIV infection.

Current opinion in infectious diseases

Davis JL, Fei M, Huang L

Epidemiology and clinical significance of pneumocystis colonization.

The Journal of infectious diseases

Morris A, Wei K, Afshar K, Huang L

HIV-associated pneumonias

BETA

Fei, M
Huang, L

Pneumocystis colonisation is common among hospitalised HIV infected patients with non-Pneumocystis pneumonia.

Thorax

Davis JL, Welsh DA, Beard CB, Jones JL, Lawrence GG, Fox MR, Crothers K, Morris A, Charbonnet D, Swartzman A, Huang L

An Official ATS Workshop Summary: Recent advances and future directions in pneumocystis pneumonia (PCP).

Proceedings of the American Thoracic Society

Huang L, Morris A, Limper AH, Beck JM

Performance of a molecular viability assay for the diagnosis of Pneumocystis pneumonia in HIV-infected patients.

Diagnostic microbiology and infectious disease

de Oliveira A, Unnasch TR, Crothers K, Eiser S, Zucchi P, Moir J, Beard CB, Lawrence GG, Huang L

Intensive care of patients with HIV infection.

The New England journal of medicine

Saccente M

Antibody response to Pneumocystis jirovecii major surface glycoprotein.

Emerging infectious diseases

Daly KR, Huang L, Morris A, Koch J, Crothers K, Levin L, Eiser S, Satwah S, Zucchi P, Walzer PD

Intensive care of patients with HIV infection.

The New England journal of medicine

Huang L, Quartin A, Jones D, Havlir DV

A need for standardized definitions for clinical studies of Pneumocystis.

The Journal of eukaryotic microbiology

Miller RF, Huang L

Pneumocystis jirovecii dihydropteroate synthase gene mutations and human immunodeficiency virus-associated Pneumocystis pneumonia.

The Journal of eukaryotic microbiology

Huang L, Welsh DA, Miller RF, Beard CB, Lawrence GG, Fox M, Swartzman A, Bensley MR, Carbonnet D, Davis JL, Chi A, Yoo BJ, Jones JL

A rose is a rose: but what about Pneumocystis pneumonia?

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

Huang L, Murray JF

Genetic differences in Pneumocystis isolates recovered from immunocompetent infants and from adults with AIDS: Epidemiological Implications.

The Journal of infectious diseases

Beard CB, Fox MR, Lawrence GG, Guarner J, Hanzlick RL, Huang L, del Rio C, Rimland D, Duchin JS, Colley DG

Severity and outcome of HIV-associated Pneumocystis pneumonia containing Pneumocystis jirovecii dihydropteroate synthase gene mutations.

AIDS (London, England)

Crothers K, Beard CB, Turner J, Groner G, Fox M, Morris A, Eiser S, Huang L

Current epidemiology of Pneumocystis pneumonia.

Emerging infectious diseases

Morris A, Lundgren JD, Masur H, Walzer PD, Hanson DL, Frederick T, Huang L, Beard CB, Kaplan JE

Pneumocystis jirovecii infection.

Thorax

Miller R, Huang L

Association of chronic obstructive pulmonary disease severity and Pneumocystis colonization.

American journal of respiratory and critical care medicine

Morris A, Sciurba FC, Lebedeva IP, Githaiga A, Elliott WM, Hogg JC, Huang L, Norris KA

Sarcoidosis following HIV infection: evidence for CD4+ lymphocyte dependence.

Chest

Morris DG, Jasmer RM, Huang L, Gotway MB, Nishimura S, King TE

Transcriptional profiles of latent human immunodeficiency virus in infected individuals: effects of Tat on the host and reservoir.

Journal of virology

Lin X, Irwin D, Kanazawa S, Huang L, Romeo J, Yen TS, Peterlin BM

Application of an mRNA-based molecular viability assay to oropharyngeal washes for the diagnosis of Pneumocystis pneumonia in HIV-infected patients. A pilot study.

The Journal of eukaryotic microbiology

Huang L, Crothers K, DeOliveira A, Eiser S, Zucchi P, Beard CB, Unnasch TR

Pneumocystis colonization in HIV-infected patients.

The Journal of eukaryotic microbiology

Huang L, Crothers K, Morris A, Groner G, Fox M, Turner JR, Merrifield C, Eiser S, Zucchi P, Beard CB

Pneumocystis dihydropteroate synthase mutations in patients with Pneumocystis pneumonia who are newly diagnosed with HIV infection.

The Journal of eukaryotic microbiology

Crothers K, Huang L, Morris A, Fox M, Groner G, Turner JR, Merrifield C, Eiser S, Friedly J, Gravari E, Zucchi P, Beard CB

Analysis of variation in tandem repeats in the intron of the major surface glycoprotein expression site of the human form of Pneumocystis carinii.

The Journal of infectious diseases

Ma L, Kutty G, Jia Q, Imamichi H, Huang L, Atzori C, Beckers P, Groner G, Beard CB, Kovacs JA

Clinical and radiographic predictors of the etiology of computed tomography-diagnosed intrathoracic lymphadenopathy in HIV-infected patients.

Journal of acquired immune deficiency syndromes (1999)

Jasmer RM, Gotway MB, Creasman JM, Webb WR, Edinburgh KJ, Huang L

Intensive care of human immunodeficiency virus-infected patients during the era of highly active antiretroviral therapy.

American journal of respiratory and critical care medicine

Morris A, Creasman J, Turner J, Luce JM, Wachter RM, Huang L

Genetic diversity of Pneumocystis carinii f. sp. hominis based on variations in nucleotide sequences of internal transcribed spacers of rRNA genes.

Journal of clinical microbiology

Nimri LF, Moura IN, Huang L, del Rio C, Rimland D, Duchin JS, Dotson EM, Beard CB

Update on the epidemiology and transmission of Pneumocystis carinii.

Microbes and infection

Morris A, Beard CB, Huang L

Pulmonary complications of HIV infection. Report of the Fourth NHLBI Workshop.

American journal of respiratory and critical care medicine

Beck JM, Rosen MJ, Peavy HH

Effect of mutations in Pneumocystis carinii dihydropteroate synthase gene on outcome of P carinii pneumonia in patients with HIV-1: a prospective study.

Lancet (London, England)

Navin TR, Beard CB, Huang L, del Rio C, Lee S, Pieniazek NJ, Carter JL, Le T, Hightower A, Rimland D

Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients.

Blood

Soumelis V, Scott I, Gheyas F, Bouhour D, Cozon G, Cotte L, Huang L, Levy JA, Liu YJ

Pneumocystis carinii cytochrome b mutations are associated with atovaquone exposure in patients with AIDS.

The Journal of infectious diseases

Kazanjian P, Armstrong W, Hossler PA, Lee CH, Huang L, Beard CB, Carter J, Crane L, Duchin J, Burman W, Richardson J, Meshnick SR

Distribution of DHPS mutations among ITS subtypes of P. carinii f. sp. hominis.

The Journal of eukaryotic microbiology

Meshnick SR, Hossler PA, Enger KS, Kazanjian P, Rest JS, Mindell D, Li B, Lee CH, Nimri LF, Carter JL, Beard CB, Huang L

Pneumocystis carinii dihydropteroate synthase genotypes in HIV-infected persons residing in San Francisco: possible implications for disease transmission.

The Journal of eukaryotic microbiology

Huang L, Friedly J, Morris AM, Carter JL, Turner JR, Merrifield C, Navin TR, Beard CB

Why does Pneumocystis carinii pneumonia still occur?

AIDS (London, England)

Huang L, Hecht FM

Geographic distribution of human immunodeficiency virus-associated Pneumocystis carinii pneumonia in San Francisco.

American journal of respiratory and critical care medicine

Morris AM, Swanson M, Ha H, Huang L

Sulfa or sulfone prophylaxis and geographic region predict mutations in the Pneumocystis carinii dihydropteroate synthase gene.

The Journal of infectious diseases

Huang L, Beard CB, Creasman J, Levy D, Duchin JS, Lee S, Pieniazek N, Carter JL, del Rio C, Rimland D, Navin TR

Permanent declines in pulmonary function following pneumonia in human immunodeficiency virus-infected persons. The Pulmonary Complications of HIV Infection Study Group.

American journal of respiratory and critical care medicine

Morris AM, Huang L, Bacchetti P, Turner J, Hopewell PC, Wallace JM, Kvale PA, Rosen MJ, Glassroth J, Reichman LB, Stansell JD

Genetic variation in Pneumocystis carinii isolates from different geographic regions: implications for transmission.

Emerging infectious diseases

Beard CB, Carter JL, Keely SP, Huang L, Pieniazek NJ, Moura IN, Roberts JM, Hightower AW, Bens MS, Freeman AR, Lee S, Stringer JR, Duchin JS, del Rio C, Rimland D, Baughman RP, Levy DA, Dietz VJ, Simon P, Navin TR

Clinical and radiographic predictors of the etiology of pulmonary nodules in HIV-infected patients.

Chest

Jasmer RM, Edinburgh KJ, Thompson A, Gotway MB, Creasman JM, Webb WR, Huang L

Multiple pulmonary nodules in AIDS: usefulness of CT in distinguishing among potential causes.

Radiology

Edinburgh KJ, Jasmer RM, Huang L, Reddy GP, Chung MH, Thompson A, Halvorsen RA, Webb RA

Performance of an algorithm to detect Pneumocystis carinii pneumonia in symptomatic HIV-infected persons. Pulmonary Complications of HIV Infection Study Group.

Chest

Huang L, Stansell J, Osmond D, Turner J, Shafer KP, Fulkerson W, Kvale P, Wallace J, Rosen M, Glassroth J, Reichman L, Hopewell P

Pseudallescheria boydii infection in AIDS.

Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association

Horton CK, Huang L, Goozé L

Decline in the rate of specific opportunistic infections at San Francisco General Hospital, 1994-1997.

AIDS (London, England)

Holtzer CD, Jacobson MA, Hadley WK, Huang L, Stanley HD, Montanti R, Wong MK, Stansell JD

High-resolution CT in the evaluation of clinically suspected Pneumocystis carinii pneumonia in AIDS patients with normal, equivocal, or nonspecific radiographic findings.

AJR. American journal of roentgenology

Gruden JF, Huang L, Turner J, Webb WR, Merrifield C, Stansell JD, Gamsu G, Hopewell PC

TB or not TB

AIDS Care

Jasmer, R
Huang, L

AIDS and the lung.

The Medical clinics of North America

Huang L, Stansell JD

Presentation of AIDS-related pulmonary Kaposi's sarcoma diagnosed by bronchoscopy.

American journal of respiratory and critical care medicine

Huang L, Schnapp LM, Gruden JF, Hopewell PC, Stansell JD

Suspected Pneumocystis carinii pneumonia with a negative induced sputum examination. Is early bronchoscopy useful?

American journal of respiratory and critical care medicine

Huang L, Hecht FM, Stansell JD, Montanti R, Hadley WK, Hopewell PC